Titlebook: Discovering and Developing Molecules with Optimal Drug-Like Properties; Allen C Templeton,Stephen R. Byrn,Thomas E. Prisin Book 2015 Ameri

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Discovering and Developing Molecules with Optimal Drug-Like Properties978-1-4939-1399-2Series ISSN 2210-7371 Series E-ISSN 2210-738X

發(fā)怨言

Ulrike R?ttger,Volker Gehrau,Joachim Preussethe atomic level. Methods for screening the glass forming ability of drug–polymer mixtures under containerless conditions, constructing phase diagrams, and extracting bonding interactions between the drug and polymer molecules are outlined.

擔(dān)心

Andres Friedrichsmeier,Silke FürstThis chapter provides an overview of the concepts of quality and risk in early development. It utilizes the FDA quality by design wheel and emphasizes the concept of learning before doing. This chapter also emphasizes stability and factors that lead to instability. Finally, this chapter addresses moisture and moisture uptake.

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encyclopedia

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Advanced X-Ray Analytical Methods to Understand Structure, Properties, and Riskthe atomic level. Methods for screening the glass forming ability of drug–polymer mixtures under containerless conditions, constructing phase diagrams, and extracting bonding interactions between the drug and polymer molecules are outlined.

開玩笑

Christian Mangold,Gerrit Seideldevelopment path utilizing minimum resources, material and time. An early assessment of developability and associated risks during drug discovery can expedite the candidate selection process, enable developable candidates to move faster into clinic and weed out non-developable candidates sooner rath

FLAX

Herbert Wanner,Mireille J. Quirinamaceutical industry. Given the complexity of modern drug discovery, this goal can only be achieved through well-designed pharmacology, pharmacokinetic, and toxicology studies resulting in the identification of exceptional development candidates. Pivotal to the success of these studies is the use of