Titlebook: Diabetes; An Old Disease, a Ne Shamim I. Ahmad Book 2013 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spring

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J. McNeil,é. Doucet,J. -P. Chaputof Langerhans. A susceptible genetic background is necessary, but not sufficient, for the development of the disease. Epidemiological and clinical observationsunderscore the importance of environmental factors as triggers of type 1 diabetes, currently under investigation. Islet-specific autoantibodi

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https://doi.org/10.1007/978-3-031-25910-4ans. Absence of insulin or insensitivity of tissues to insulin leads to hyperglycaemia and elevated plasma fatty acid concentration. Hyperglycaemia can lead to modification of protein functions which can contribute to accelerated atherosclerosis. The latter is the pathological condition which underl

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Federica Buongiorno,Xenia Chiaramontetations, such as activation of the KRAS2 oncogene, inactivation of the tumor-suppressor gene CDKN2A, inactivation of the tumor-suppressor gene TP53 and deleted in pancreatic cancer 4 (.) gene defects are seen in those with pancreatic cancer. Approximately 80%of those patients, diagnosed with pancrea