Titlebook: Deoxynucleoside Analogs in Cancer Therapy; Godefridus J. Peters (Professor of Medical Oncolog Book 2006 Humana Press 2006 HIV.cancer.cance

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https://doi.org/10.1007/3-540-26620-8h as non-small cell lung carcinoma and pancreatic and bladder cancer. In this chapter, we summarize the role of the key enzymes in its metabolic activation and deactivation pathways, the role of the various targets, the associated mechanisms of acquired and inherent resistance, and the changes in DN

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Komponenten des thermischen Apparatebaus,e, fluoromethylenedeoxycytidine) can synergistically enhance ionizing radiation-induced cell killing. These analogs are able to radiosensitize a wide variety of tumor cell types in vitro and several have proven clinical efficacy as well. They share a requirement for intracellular metabolism to phosp

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https://doi.org/10.1007/978-3-662-10219-0ravenously administered nucleoside analogs cytosine arabinoside (ara-C) and fludarabine phosphate (F-ara-A) in pediatric patients with leukemias. A description of the major NONMEM tasks as well as the statistical models has been given for these drugs. Two pharmacokineticpharmacodynamic (PK-PD) model

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Godefridus J. Peters (Professor of Medical OncologIncludes supplementary material:

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Cancer Drug Discovery and Developmenthttp://image.papertrans.cn/d/image/265686.jpg

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