Titlebook: DNA Methylation and Cancer Therapy; Moshe Szyf Book 2005 Springer-Verlag US 2005 DNA.Expression.Microarray.Purine.enzymes.gene expression.

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https://doi.org/10.1007/978-3-642-24996-9methylation of CpG islands of tumor suppressor genes associated with their transcriptional silencing. The target genes are distributed in all cellular pathways (apoptosis, DNA repair, cell cycle, cell adherence, etc.). They are “classical” tumor suppressor genes with associated familial cancers (BRC

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https://doi.org/10.1007/978-3-642-24996-9er than histone acetylation, poly(ADP-ribosyl)ation, participates in the establishment and maintenance of methylation-free regions of chromatin. In fact, several lines of in vitro and in vivo evidence have shown that poly(ADP-ribosyl)ation is involved in the control of DNA methylation pattern, prote

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https://doi.org/10.1007/978-3-642-24996-9cleosides and their corresponding nucleobases are the fundamental building blocks of many biological systems and as a result, have been extensively investigated due to their inherent structural resemblance to the naturally occurring nucleosides and nucleobases. Due to the intertwined relationship be