Titlebook: DNA Methylation Protocols; J?rg Tost Book 2018Latest edition Springer Science+Business Media, LLC 2018 DNA.cytosines.gene expression.chrom

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https://doi.org/10.1007/978-3-031-47130-8h the locus-specific and the genome-wide level. It has become increasingly clear, however, that comprehension of the functional interactions between epigenetic mechanisms is critical for understanding how cellular transcription programs are regulated or deregulated during normal and disease developm

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https://doi.org/10.1007/978-1-4939-7481-8DNA; cytosines; gene expression; chromatin remodeling; molecular assays; pyrosequencing; single CpG positi

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DNA Methylation Protocols978-1-4939-7481-8Series ISSN 1064-3745 Series E-ISSN 1940-6029

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A Summary of the Biological Processes, Disease-Associated Changes, and Clinical Applications of DNA ression through chromatin structure. It closely interacts with histone modifications and chromatin remodeling complexes to form the local genomic and higher-order chromatin landscape. DNA methylation is essential for proper mammalian development, crucial for imprinting and plays a role in maintainin

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Quantification of Global DNA Methylation Levels by Mass Spectrometry were based on the use of high-performance separation technologies and UV detection. However, the recent development of protocols using mass spectrometry for the detection has increased sensibility and permitted the precise identification of peak compounds based on their molecular masses. This allow