Titlebook: Cytokine Protocols; Marc Ley Book 2004 Humana Press 2004

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,Detection of Cytokine Signal Transduction “Cross-Talk” in Leukocyte Activation,ell types (.). Although most cytokines are soluble proteins, they can infrequently be found expressed at the cell surface. Cytokines are ligands for one or more cell surface receptors that mediate communication with intracellular signaling, metabolic, and gene regulation pathways. Cells respond to t

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,Modulation of the Interferon-γ Signal by Transfection of Cells with an Antisense-RNA Expressing Vecfic proteins. Application of highly specific inhibitors of these paths is the basis for their unraveling, including the identification of parallel paths and the occurrence of “crosstalk.” The elucidation of specific inhibitors also has possible medical applications.

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