Titlebook: Current Topics in Innate Immunity II; John D. Lambris,George Hajishengallis Book 2012 The Editor(s) (if applicable) and The Author(s), und

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?konomie der Medien und des Mediensystemsogenic inhibitors. However, these treatments do not address the underlying cause of many of these diseases. A clear understanding of the cellular and molecular mechanisms could bring a major shift in our approach to disease treatment and prevention.

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0065-2598 k is an excellent source of information for researchers and clinicians with interests in immunology, host-microbe interactions, and infectious and inflammatory diseases.978-1-4614-2952-4978-1-4614-0106-3Series ISSN 0065-2598 Series E-ISSN 2214-8019

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Pentraxins in Humoral Innate Immunity,se. The innate immune system comprises both a cellular and a humoral arm. Components of the humoral arm include soluble pattern recognition molecules (PRMs) that recognise pathogens associated molecular patterns (PAMPs) and initiate the immune response in coordination with the cellular arm, therefor

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Galectins as Pattern Recognition Receptors: Structure, Function, and Evolution,s, and fungi. Since their discovery in the 1970s, their biological roles, initially understood as limited to recognition of carbohydrate ligands in embryogenesis and development, have expanded in recent years by the discovery of their immunoregulatory activities. A gradual paradigm shift has taken p

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A Conserved Host and Pathogen Recognition Site on Immunoglobulins: Structural and Functional Aspectns. This site is located at the junction of two constant domains in the antibody heavy chains and produces a large shallow cavity formed by loops of the CH2 and CH3 domains in IgG and IgA (CH3 and CH4 domains in IgM). Crystal structures have been determined for complexes of IgG-Fc and IgA-Fc with a