Titlebook: Cortical Spreading Depression of Leao; From Mitochondrial F Avraham Mayevsky,Judith Sonn Book 2022 The Editor(s) (if applicable) and The Au

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Single Point and Multisite Monitoring of Brain NADH Fluorescence Under CSD, of the fiber-optic-based technology to monitor brain NADH redox state, we exposed the rat brain to CSD. Our monitoring system allowed us to study the effect of CSD on mitochondrial function as well as other physiological parameters in the . small animal model using the flexible fiber-optic probe ce

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Spontaneous Development of CSD Related to Brain Pathophysiological Conditions,between the availability of oxygen and the development of CSD may involve the leakage of potassium from the intracellular to the extracellular compartment in the cerebral cortex tissue. The interaction between the level of carbon dioxide in the breathing mixture in the hyperbaric chamber will be dem

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The Effects of Brain Metabolic and Other Perturbations on the Responses to Induced CSD, level of potassium. The metabolic perturbations included oxygen availability (mild hypoxia, hyperoxia, and partial ischemia) hypothermia, anesthesia, and the age of the rats. In the studies described in this chapter, we used the multiparametric monitoring systems as well as multisite system measuri

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Clinical Monitoring of Cortical Spreading Depression (CSD) in the Human Brain,rious surgical procedures including long-term monitoring in the ICU. The brain was the main organ monitored in neurosurgical patients who underwent vascular procedures or treated in the ICU. Our studies led to the first discovery of the responses to CSD in neurosurgical patient in the ICU. Special d

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CSD and the LifenLight Score (LLS),tation. In this chapter we are presenting the evolution of the concept named initially “brain vitality.”.To develop the brain metabolic score or LifenLight Score (LLS), we used the four parameter monitoring system including mitochondrial function (NADH fluorescence), cerebral blood flow and volume,

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