Titlebook: Copper and Bacteria; Evolution, Homeostas Marc Solioz Book 2018 The Author(s) 2018 Bacteria.Copper Homeostasis.Contact Killing.Gene Regulat

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Marc SoliozBroadens understanding of copper homeostasis and toxicity.Outlines the evolution of copper use by cells.Elucidates the contact killing of bacteria by metallic copper

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SpringerBriefs in Molecular Sciencehttp://image.papertrans.cn/c/image/238172.jpg

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Motilin

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The Death of the Transcendental Person, keep intracellular copper at safe levels. However, under conditions of excess environmental copper, homeostatic system become overloaded and intracellular copper rises to toxic levels. Possible toxic effects of copper span a range of mechanisms and it cannot be known with certainty which mechanism

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The First Person and the Transcendental I,ne (founding member CopZ), and a copper-responsive regulator (founding member CopY) which regulates the expression of these functions. GSH works as a back-up protective system. These four components are also part of the more complex copper homeostatic mechanism of Gram-negative organisms, discussed