Titlebook: Controversies in the Management of Gynecological Cancers; Jonathan A. Ledermann,Carien L. Creutzberg,Michael Book 2014 Springer-Verlag Lon

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Introduction to Phase-Reference Mapping and controversies including surgical staging and surgical and medical treatments. We provide a critical overview of the most debated and controversial aspects of this challenging disease. In surgery, we focus on confidence in initial staging and the impact of under-assessment and undertreatment, th

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Very Long Baseline Interferometryous carcinoma. High-grade serous carcinoma causes the vast majority of ovarian cancer deaths. This classification correlates with a variety of distinctive clinical, epidemiological, molecular, and behavioral features. This cell type-specific approach is a valuable framework for understanding the bio

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Very Long Baseline Interferometryed, with emphasis on the controversial issues and pro/con discussions. Ongoing issues of debate for which future trials should provide evidence are highlighted. Risk-based treatment selection is emphasized, with the aim of sparing many patients with low-risk endometrial cancer unnecessary toxicities

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https://doi.org/10.1007/978-94-009-2717-9to further individualize therapy. Perhaps, hormonal therapy can be seen as the first biological targeted agent followed by anti-VEGF agents and mTOR inhibitors. Chemotherapy continues to be the mainstay in the treatment of endometrial cancer despite the development of these novel agents. In the futu

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https://doi.org/10.1007/978-94-009-2717-9ny developed countries. Because rates of cervical cancer peak in older women, vaccination is expected to take some years to substantially reduce the overall rates of invasive cervical cancer, but in countries with high rates of vaccination coverage, cancer rates in younger women are expected to drop

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https://doi.org/10.1007/978-94-009-3081-0 for rare cancers, patient accrual to trials is frequently prolonged, there is no consensus about the most efficient clinical trial design methodology, and national regulatory requirements currently significantly impair the ability to conduct international trials. In this chapter, we discuss the pro