Titlebook: Controversies in the Management of Gynecological Cancers; Jonathan A. Ledermann,Carien L. Creutzberg,Michael Book 2014 Springer-Verlag Lon

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https://doi.org/10.1007/978-94-009-3081-0ed (stages III–IV) epithelial ovarian cancer (EOC). It is known that the quality of surgery is one of the most important factors affecting the outcome of women with advanced EOC. We have reviewed the European population-based literature, focusing especially on studies published in the last 10 years,

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https://doi.org/10.1007/978-94-009-3081-0ment for these patients has always been up-front surgery, with the aim of achieving complete macroscopic removal of tumor followed by chemotherapy. In 2010, the results from a large phase III randomized study performed by the EORTC suggested no difference in survival whether the chemotherapy was giv

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P. T. Tueller (Professor of Range Ecology)sease in a mean time of 15 month; only 30–40 % will survive 5 years. Several treatment strategies have been evaluated for prolonging the time free of disease and reducing the risk of death. Maintenance treatment, i.e., continuation of primary chemotherapy in patients without progression of the disea

concise

P. T. Tueller (Professor of Range Ecology) and this has obvious prognostic importance. Tumor grade and histology are important when considering this pattern of spread, but the evidence for a survival benefit for lymphadenectomy is scarce, there has been no uniform agreement on the extent of lymphadenectomy, and long-term follow-up of patien

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S. G. Leonard,R. L. Miles,P. T. Tuellerfication is the introduction of the sentinel node procedure for patients with early stage vulvar cancer. The introduction of the sentinel node procedure brought about a major decrease in treatment-related morbidity. However, some controversies remain and these will be discussed in this chapter.

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J. T. A. Verhoeven,W. Koerselman,B. Beltmanity therapy that integrates (chemo)radiotherapy with less extensive surgery is well accepted in order to avoid stoma formation; however, the roles for adjuvant therapy after surgical management of both the primary and nodal disease are poorly defined. To avoid exenterative surgery in advanced diseas

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978-1-4471-7170-6Springer-Verlag London 2014