Titlebook: Computational Methods for SNPs and Haplotype Inference; DIMACS/RECOMB Satell Sorin Istrail,Michael Waterman,Andrew Clark Conference proceed

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A Coalescent-Based Approach for Complex Disease Mappingthis process, linkage mapping, have been addressed, but data analysis for LD-mapping remains extremely challenging. In this article we describe our work on developing a full statistical framework for LD mapping based on a population genetics model known as the coalescent.

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Haplotyping as Perfect Phylogenyes established results from matroid and graph theory. In this work, we present an O(nm.) algorithm for this problem using elementary techniques. We also describe a linear space representation for representing all possible solutions, and provide a formula for counting the number of possible solutions.

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Wolfgang Skorupa,Heidemarie Schmidt the information content of the full set of sequences. We develop methods for these approaches based on a prior method we developed for predicting piece-wise shared ancestry of haploid sequences. We apply these methods to a case study of two genetic regions with very different levels of sequence div

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oracle

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