Titlebook: Chemokine Receptors in Cancer; Amy M. Fulton Book 2009 Humana Press 2009 angiogenesis.cytokines.metastasis.prostate cancer.tumor

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G. Barucchi,G. Ponzano,T. Reggers that affect tumor growth, invasion, and metastasis. One group of such factors are CXC chemokines, which are a subset of chemotactic cytokines which, through their receptors, have angiogenic or angiostatic properties. This review will discuss our current understanding of the various functional rol

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CXC Chemokines in Cancer Angiogenesis,ocesses. Angiogenesis, or the process of new blood vessel growth, is critical to many physiologic and pathologic processes, including tumorigenesis. In this chapter, we review the role of chemokines in cancer angiogenesis and angiostasis.

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The CCL5/CCR5 Axis in Cancer,5 and CCR5 in patients, their associations with disease course and experiments that were performed in animal model systems in order to decipher the roles of the CCL5/CCR5 axis in tumor growth and metastasis. In addition, we describe possible mechanisms mediating the activity of this pair in specific

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