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Titlebook: Central Nervous System Leukemia; Prevention and Treat Renato Mastrangelo,David G. Poplack,Riccardo Ricca Book 1983 Martinus Nijhoff Publish

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發(fā)表于 2025-3-21 18:43:48 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Central Nervous System Leukemia
副標(biāo)題Prevention and Treat
編輯Renato Mastrangelo,David G. Poplack,Riccardo Ricca
視頻videohttp://file.papertrans.cn/224/223192/223192.mp4
叢書(shū)名稱Developments in Oncology
圖書(shū)封面Titlebook: Central Nervous System Leukemia; Prevention and Treat Renato Mastrangelo,David G. Poplack,Riccardo Ricca Book 1983 Martinus Nijhoff Publish
描述In the past 10 to IS years there has been dramatic improvement in the survival of children with acute lymphoblastic leukemia. At the present time, over 50% of children with this disease will be alive and free of their disease at least 5 years from the time of their initial diagnosis. Although a number of factors have contributed to this improvement, perhaps none has been as important as the institution of central nervous system preventive therapy (eNS prophylaxis). However, despite the efficacy of eNS prophylaxis, the prevention and treatment of central nervous system leukemia continues to pose a formidable clinical challenge to the pediatric oncologist. Although successful in most cases, eNS preventive therapy remains ineffective for a small but significant subset of patients at high risk for developing eNS disease. Moreover, it has become increasingly evident that some methods of eNS preventive therapy are associated with long-term, adverse eNS sequelae. Thus, considerable controversy exists regarding the optimal method of eNS prophylaxis. Treatment of the patient who develops overt meningeal leukemia has not been as successful and continues to pose a major clinical challenge. De
出版日期Book 1983
關(guān)鍵詞chemotherapy; leukemia; pathology; prevention; radiation therapy
版次1
doihttps://doi.org/10.1007/978-94-009-6708-3
isbn_softcover978-94-009-6710-6
isbn_ebook978-94-009-6708-3
copyrightMartinus Nijhoff Publishers, Boston 1983
The information of publication is updating

書(shū)目名稱Central Nervous System Leukemia影響因子(影響力)




書(shū)目名稱Central Nervous System Leukemia影響因子(影響力)學(xué)科排名




書(shū)目名稱Central Nervous System Leukemia網(wǎng)絡(luò)公開(kāi)度




書(shū)目名稱Central Nervous System Leukemia網(wǎng)絡(luò)公開(kāi)度學(xué)科排名




書(shū)目名稱Central Nervous System Leukemia被引頻次




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書(shū)目名稱Central Nervous System Leukemia讀者反饋




書(shū)目名稱Central Nervous System Leukemia讀者反饋學(xué)科排名




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沙發(fā)
發(fā)表于 2025-3-21 20:20:04 | 只看該作者
Central Nervous System Prophylaxis for Therapy of Acute Lymphocytic Leukemia,at cure is now a realistic goal of treatment (1). There has been increasing emphasis in recent years, therefore, on the late consequences of the disease and its therapy. These late consequences include possible organ damage, endocrine dysfunction, second malignancies, central nervous system (CNS) dy
板凳
發(fā)表于 2025-3-22 01:46:50 | 只看該作者
Reduction in Central Nervous System Leukemia with a Pharmaco-kinetically derived Intrathecal-Methot that the primary volume of distribution of IT MTX approximated the extracellular-fluid volume of the central nervous system (CNS) (1). The modified dosage regimen was subsequently confirmed to be less neurotoxic (2), with more consistent cerebrospinal-fluid (CSF) MTX concentrations than dosage base
地板
發(fā)表于 2025-3-22 08:05:34 | 只看該作者
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發(fā)表于 2025-3-22 12:18:49 | 只看該作者
,Prophylaxis of Central Nervous System Leukaemia: British Experience, 1970–80, the United Kingdom, one of the variables was ‘prophylactic’ treatment against central nervous system (CNS) leukaemia. In view of the overwhelming evidence for the efficacy of such treatment (1, 2), all patients entered to subsequent trials have received some form of CNS prophylaxis. This report com
6#
發(fā)表于 2025-3-22 13:29:17 | 只看該作者
The Norwegian Methotrexate Study in Childhood Acute Lymphocytic Leukemia,elsewhere in this book, have indicated the potential adverse effects of the combination of cranial irradiation and intrathecal methotrexate. Therefore we have tried to avoid prophylactic cranial irradiation in our treatment protocol.
7#
發(fā)表于 2025-3-22 18:14:44 | 只看該作者
Therapy Related Central Nervous System Diseases in Children with Acute Lymphocytic Leukemia,nally irradiation to enlarged viscera and mediastinal masses, the majority of children who developed this disease died during the first six months following diagnosis, and rarely did a child survive beyond nine months (1). Farber’s success, reported in 1948, in achieving temporary remissions in five
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發(fā)表于 2025-3-23 00:18:54 | 只看該作者
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發(fā)表于 2025-3-23 03:21:49 | 只看該作者
Evaluation of Adverse Sequelae of Central Nervous System Prophylaxis in Acute Lymphoblastic Leukemin with acute lymphoblastic leukemia. Anatomic abnormalities (defined by CT brain scan), neuroendocrine damage, as well as neurological and intellectual dysfunction have all been reported in patients who have received central nervous system propylaxis, usually in the form of cranial radiation and int
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發(fā)表于 2025-3-23 09:14:14 | 只看該作者
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