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Titlebook: Central Cholinergic Synaptic Transmission; Michael Frotscher,Ulrich Misgeld Book 1989 Birkh?user Verlag 1989 Nervous System.Parkinson.anat

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發(fā)表于 2025-3-21 18:52:26 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Central Cholinergic Synaptic Transmission
編輯Michael Frotscher,Ulrich Misgeld
視頻videohttp://file.papertrans.cn/224/223173/223173.mp4
叢書名稱Experientia Supplementum
圖書封面Titlebook: Central Cholinergic Synaptic Transmission;  Michael Frotscher,Ulrich Misgeld Book 1989 Birkh?user Verlag 1989 Nervous System.Parkinson.anat
描述Our knowledge of cholinergic synaptic transmission in the peripheral nervous system (PNS) has expanded enormously since the early 1930‘s, at which time O. Loewi discovered chemical neurotransmission through acetylcholine (ACh) and the pharmacological actions of ACh were described by H. Dale and his colleagues. Description of ACh‘s actions and receptors in various parts of the brain was followed by a detailed analysis of ACh‘s synthesis, release mechanism, removal from the synaptic cleft, modes of agonist-receptor interactions, properties of regulated conductances and of the pre-and postsynaptic modulation of cholinergic synapses. Our knowledge has been increasingly consolidat- ing, leading us to the recent clarification of the structure of the periph- eral nicotinic receptor-ion channel and its functional properties. It is appropriate to maintain the claim that the fundamentals of our under- standing of synaptic transmission come from studies on cholinergic synapses in the PNS. Contrastingly, views held on the role of cholinergic synapses in the mammalian central nervous system (CNS) are extremely controversial, although it has been clear for some time that ACh is present in the br
出版日期Book 1989
關鍵詞Nervous System; Parkinson; anatomy; cortex; forebrain; neurons
版次1
doihttps://doi.org/10.1007/978-3-0348-9138-7
isbn_softcover978-3-0348-9922-2
isbn_ebook978-3-0348-9138-7Series ISSN 1664-431X Series E-ISSN 2504-3692
issn_series 1664-431X
copyrightBirkh?user Verlag 1989
The information of publication is updating

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沙發(fā)
發(fā)表于 2025-3-21 22:38:36 | 只看該作者
Opposing effects of acetylcholine on the two classes of voltage-dependent calcium channels in hippocActivating rather than depressive effects of Ach were observed on the low voltage-activated component of Ca currents. This effect was also antagonized by atropine but is not mediated by a PTX-sensitive G-protein.
板凳
發(fā)表于 2025-3-22 04:14:46 | 只看該作者
J.-Y. Reginster,J.-P. Pelletier,L. Crasborn reticular nucleus-thalamocortical circuitry. We further suggest that the NB system may serve as a structural basis for the concept of the generalized activation described by Moruzzi and Magoun (1949).
地板
發(fā)表于 2025-3-22 08:21:49 | 只看該作者
5#
發(fā)表于 2025-3-22 08:56:34 | 只看該作者
The cholinergic nucleus basalis: A key structure in neocortical arousal reticular nucleus-thalamocortical circuitry. We further suggest that the NB system may serve as a structural basis for the concept of the generalized activation described by Moruzzi and Magoun (1949).
6#
發(fā)表于 2025-3-22 13:39:08 | 只看該作者
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發(fā)表于 2025-3-22 19:25:45 | 只看該作者
1664-431X which time O. Loewi discovered chemical neurotransmission through acetylcholine (ACh) and the pharmacological actions of ACh were described by H. Dale and his colleagues. Description of ACh‘s actions and receptors in various parts of the brain was followed by a detailed analysis of ACh‘s synthesis,
8#
發(fā)表于 2025-3-23 01:12:16 | 只看該作者
M. Meister,C. Hetru,J. A. Hoffmannd by the reduction of an outward current termed I. through the activation of a second muscarinic receptor subtype. While hippocampal slow EPSPs might be involved in information processing across hippocampal pathways, muscarinic modulation in the neostriatum consists of a presynaptic tuning of nicotinic fast synaptic transmission.
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發(fā)表于 2025-3-23 03:17:39 | 只看該作者
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發(fā)表于 2025-3-23 06:00:18 | 只看該作者
Operative onkologische Dermatologiex experiments indicate that this membrane protein is different from the toxin-insensitive nAChR present in vertebrate neurons..Crosshybridization with a . nAChR cDNA probe allowed isolation of a cholinergic receptor cDNA (ARD) from the . CNS. Analysis of the corresponding gene, its transcripts and the ARD protein are presented here.
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