Titlebook: Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres; John M. G. Davis,Marie-Claude Jaurand Conference proceedings 199

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Carcinogenic Effects in Rats of Exposure to Different Minerals from Metallic Mine Ores, Radon and Rarganic materials might be related to their surface reducing properties allowing the formation of activated species of oxygen. The potential carcinogenic or cocarcinogenic properties of 4 minerals present in the ores of metallic mines (nemalite, a contaminant of the Quebec chrysotile, biotite, presen

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Augmentation in the Differential Oxidative DNA-Damage by Asbestos in Presence of H2O2 and Organic Pessed in terms of the destabilization of secondary structure of DNA, damage to deoxyribose sugar and DNA fidelity which were measured respectively by S-1 nuclease hydrolysis, formation of thiobarbituric acid (TBA) — reacting species and melting temperature (Tm) profile using calf thymus DNA. S-1 nucl

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DNA and Chromosome Damage Produced by Some Minerals and Man Made Particles on Rat Pleural Mesothelelevant to investigate the effects of particles on the cell structures carrying the genes. Several . assays can be used allowing the detection of effects of potential carcinogens at the DNA and chromosome level. To use these assays as predictive or mechanistic models, one important point is to deter

摘要

Evaluation of Proinflammatory Cytokine Expression in Alveolar Macrophages and in the Lung of Pneumocted in bronchoalveolar lavage (BAL) and lung tissue from pneumoconiotic patients. BAL was collected from 19 simple pneumoconiosis (SP) and 8 progressive massive fibrosis (PMF), while lung parenchyma specimen were obtained from 1 SP and 3 PMF. TNF and IL-6 mRNA expression was assessed using . hybridi

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