Titlebook: Cellular Primary Immunodeficiencies; Mario Milco D‘Elios,Cosima Tatiana Baldari,Frances Book 2021 Springer Nature Switzerland AG 2021 T Ce

BLAND

Needles, Sutures, and Instruments,estations associated with PID categorized as (i) SCID/CID, (ii) LOCID, (iii) APECED, (iv) IPEX, (v) hypogammaglobulinemias, (vi) immunodysregulation disorders, and (vii) ALPS, describing each prototypical molecular defect and delving into the mechanisms that contribute to the development of AI.

BINGE

travail

IPEX Syndrome and IPEX-Related Disorders,gs biology or Tregs unrelated, and acting at different levels during immune response regulation. The clinical similarities and differences between these inborn errors of immunity, along with their molecular cause, diagnosis, and treatment options, will be discussed.

自負的人

Lung in Cellular Immunodeficiencies,d lung complications (see Table .); lung complications (see Table .) in PID can be broadly divided in infections and chronic complications. In this chapter, we review the main clinical and epidemiological features associated with lung involvement in PID.

蔓藤圖飾

Autoimmunity in Cellular Immunodeficiencies,estations associated with PID categorized as (i) SCID/CID, (ii) LOCID, (iii) APECED, (iv) IPEX, (v) hypogammaglobulinemias, (vi) immunodysregulation disorders, and (vii) ALPS, describing each prototypical molecular defect and delving into the mechanisms that contribute to the development of AI.

constellation

清楚

商業(yè)上

Phenocopies of Primary Immunodeficiency Diseases,er, they are caused by somatic mutations or autoantibodies against cytokines rather than germline monogenic defects. They are classified as a separate group by the International Union of Immunological Societies (IUIS).

軍火

Dysfunctional Immune Synapses in T Cell Immunodeficiencies,pecific MHC-associated antigen, T lymphocytes assemble a highly organized intercellular junction, referred to as the immune synapse, on which T cell activation, proliferation, and differentiation crucially depend. Immune synapse assembly and function are impaired in a subgroup of human immunodeficie

屈尊

Mucosal Immunity in Primary Immunodeficiencies,anical and chemical means, they prevent invasion by pathogens. The mucosal immune system consists of an innate and acquired system that interact with each other in a complex way. The mucosal immune system also has the delicate task of differentiating between pathogens and non-pathogens. The T and B