Titlebook: Cell Death Signaling in Cancer Biology and Treatment; Daniel E. Johnson Book 2013 Springer Science+Business Media New York 2013 Cancer.Can

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Harnessing Death Receptor Signaling for Cancer Treatment,ne side and cell proliferation on the other side toward survival promotes tumor formation. The death receptor (extrinsic) pathway represents one of the major apoptosis signaling cascades, which links exogenous stimuli via transmembrane surface receptors to the intracellular signaling machinery that

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New Agents and Approaches for Targeting the RAS/RAF/MEK/ERK and PI3K/AKT/mTOR Cell Survival Pathwayutations in intrinsic pathway components. Upstream mutations in one signaling pathway or even in downstream components of the same pathway can alter the sensitivity of the cells to certain small molecule inhibitors. These pathways have profound effects on proliferative, apoptotic, and differentiatio

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2625-2902 clinical approaches.Features development and application of A key goal in the treatment of cancer is to achieve selective and efficient killing of tumor cells. The aim of .Cell Death Signaling in Cancer Biology and Treatment. is to describe state-of-the-art approaches and future opportunities for ac

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