Titlebook: Cardiac Glycosides 1785–1985; Biochemistry — Pharm Erland Erdmann,K. Greef,J. C. Skou Conference proceedings 1986 Springer-Verlag Berlin He

Clumsy

The human red blood cell: A model for ouabain receptor regulation in the heart?sults were obtained:.The differences in ouabain receptor regulation in erythrocytes and heart muscle cells may be attributable to the lack of a “sodium pump reserve” in erythrocytes. Such variations in receptor regulation indicate that the human erythrocyte is not a suitable model for the ouabain re

躲債

SLUMP

The ouabain receptor in the myocardium and conduction system of the sheep hearte molecular basis for the increased digitalis sensitivity of the conducting system. .H-ouabain binding has the following characteristics:.(1) in sheep left ventricular cell membranes, specific binding was of high affinity (K. 1.9 × 10.M at 37°); was coincident with an inhibition of (Na. + K.)-ATPase

Keratectomy

Electrophysiological effects of cardiac glycosidesce an initial prolongation of the action potential due to inhibition of the electrogenic Na-K pump current. This is then followed by a gradual decrease of action potential duration to less than control length. The origin of this decrease is uncertain. Cardiac glycosides also produce a transient depo

哪有黃油

PRO

Rat cardiac hypertrophy: contribution of heteregeneous digitalis receptor formson by ouabain occurs in the same range of concentrations as pharmacologically active doses in various species including rat. In this species, it has been shown that the sensitivity of Na/K-ATPase to ouabain was heterogeneous with high and low sensitivity forms (K. 10., 10. M and 10., 10. M, respecti

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音樂等

overreach

The influence of ,-tocopherol-nicotinate (Renascin,) on cardiac glycoside effectsto guinea-pig heart homogenate was investigated...-tocopherol-nicotinate and dodecanoic acid had an inhibitory effect on the positive inotropic action of digoxin but not on that of ouabain. This effect was parallel to their inhibitory effect of digoxin and not ouabain binding to heart homogenate. Th

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