Titlebook: Cancer Immunotherapy; Paradigms, Practice Tyler J. Curiel Book 2013 Springer Science+Business Media New York 2013 Anti-tumor immunity.Canc

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Myeloid-Derived Suppressor Cells in Cancer: Mechanisms and Therapeutic Perspectives the production of various intermediates such as reactive nitrogen species and reactive oxygen species that can suppress T cell function. Here, we review recent concepts on how MDSC can regulate T cell function in cancer and other chronic inflammatory diseases and suggest possible therapeutic interventions to overcome this inhibitory effect.

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