Titlebook: Blistering Diseases; Clinical Features, P Dédée F. Murrell Book 2015 Springer-Verlag Berlin Heidelberg 2015 Epidermolysis bullosa.Immunoflu

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Apoptosis and Signaling in Bullous Diseases: Pemphiguss (acantholysis). By an as yet unknown mechanism, autoantibodies are produced and bind to keratinocyte proteins. The best characterized pemphigus autoantigens are the desmosome cadherins desmoglein 3 and desmoglein 1. Pemphigus autoantibodies are pathogenic; passive transfer of dsg1 and dsg3 IgG aut

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How to Take a Skin Biopsy Correctly to Diagnose Epidermolysis Bullosa and Autoimmune Bullous Diseaseppropriate clinical setting with routine histology consistent wtih an AIBD. Diagnostic modalities for epidermolysis bullosa (EB) include immunofluorescence antigenic mapping (IFM), transmission electron microscopy (TEM), and genetic mutational analysis. Of these, the most preferred is IFM. Because a

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ELISA Testing and Immunoblottingsts, enzyme-linked immunosorbent assay (ELISA) and immunoblotting are now two major methods to diagnose autoimmune bullous diseases. Two major groups of autoimmune bullous disease are pemphigus and pemphigoid. The major autoantigens of pemphigus are desmogleins, and those of pemphigoid are BP180 and

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Book 2015g of the pathogenetic mechanisms to management of the individual diseases. The aim is to provide a detailed reference for dermatologists who care for patients with these conditions and a useful “one-stop information shop” for specialists outside of dermatology. The book opens by describing the struc

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