| 期刊全稱(chēng) | Biosynthesis | | 期刊簡(jiǎn)稱(chēng) | Polyketides and Vita | | 影響因子2023 | Finian J. Leeper,John C. Vederas | | 視頻video | http://file.papertrans.cn/189/188618/188618.mp4 | | 發(fā)行地址 | Very affordable price.For the personal libraries of graduates and scientists working at the cutting edge of academic, industrial and pharmaceutical research.Includes supplementary material: | | 學(xué)科分類(lèi) | Springer Desktop Editions in Chemistry | | 圖書(shū)封面 |  | | 影響因子 | The present volume is the first of two planned to provide state-of-the-art expert reviews of central topics in modern natural products chemistry and secondary metabolism. Many scientists not directly involved in these areas still view the field of natural products as focused primarily on the isolation,structure elucidation, and cataloging of new compounds (i. e. “grind and find”),or on their chemical synthesis. However,two revolutions in experimental techniques since the early 1950’s have completely transformed the understanding of chemical and biological relationships between highly diverse natural products. The first was the use isotopes to label precursors and follow the fate of key atoms during biochemical transformations to a final product. Advances in methodology that began in the mid-1970’s,especially using NMR to detect stable isotopes,dramatically expanded the level of mechanistic detail available to study in vivo conversions of secondary metabolites. The second revolution started in the late 1980’s as researchers developed methods to identify,purify and genetically manipulate individual enzymes - sponsible for the intricate steps leading to complex natural products. This | | Pindex | Book 1998 |
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