Titlebook: Biosynthesis; Polyketides and Vita Finian J. Leeper,John C. Vederas Book 1998 Springer-Verlag Berlin Heidelberg 1998 Biosynthese.Expression

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Biosynthesis of Vitamin B12, to hydrogen-obyrinic acid in ., which has revealed some beautiful and totally unexpected chemistry. A short section then describes the many similarities and some differences in the chemistry used by the micro-aerophilic organism . for the synthesis of coenzyme B. compared with that seen in the aero

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https://doi.org/10.1007/978-3-319-69404-7mation on key steps as well as producing interesting analogues of the natural metabolites. Application of .N labelling in conjunction with other isotopes, e.g. .C and .O, is illustrated by studies on the formation of 3-nitropropanoic acid. Recent work on the enzymes of polyketide biosynthesis also m

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A GRASP for the Minimum Cost SAT Problemdified by post-PKS enzymes, including glycosidases, methyltransferases, acylases and oxidative enzymes, to produce still greater diversity. In this article the development of the field will be exemplified by a detailed discussion of the archetypal example of erythromycin A biosynthesis. This will th

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The Biosynthesis of Aliphatic Polyketides,mon pathway in which units derived from acetate, propionate and butyrate are condensed onto a growing chain, which is initiated from a range of structurally varied carboxylic acid starter units, in a process closely resembling fatty acid biosynthesis. The intermediates remain bound to the polyketide

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Cofactor Biosynthesis: A Mechanistic Perspective,actors is now a thoroughly studied area. In contrast, the chemistry of cofactor biosynthesis is still relatively underdeveloped. In this review the biosynthesis of nicotinamide adenine dinucleotide, riboflavin, folate, molyb-dopterin, thiamin, biotin, lipoic acid, pantothenic acid, coenzyme A, S-ade

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