Titlebook: Biophysics of the Pancreatic β-Cell; Illani Atwater,Eduardo Rojas,Bernat Soria Book 1986 The Editor(s) (if applicable) and The Author(s),

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https://doi.org/10.1007/978-3-031-56118-4al events in “stimulus-release coupling”.. However, very recent development of patch clamp techniques. has made it possible to undertake a detailed characterization of membrane ionic conductances present in these cells, and to elucidate their precise role in the regulation of secretion. Among the di

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(Mariana Rondón. 2013, Venezuela)ry cells which allows extracellular Ca. to penetrate them and trigger the catecholamine ejection process.” The formation accumulated since then can be summarized in the diagram of the sequence of events taking place during the secretory cycle depicted in Fig. 1.

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https://doi.org/10.1007/978-3-031-56118-4e secretory and electrical responses are furthermore known to be closely correlated.. From membrane potential recordings obtained with conventional intracellular electrodes and from flux measurements at least three types of currents have been postulated..

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Americanization and Resistance, The RINm5F cell line was developed from an insulinoma induced initially in a rat and then transplanted through mice before being established as a continuous cell line.. The secretion of insulin by RINm5F cells can be stimulated by secretagogues such as glyceraldehyde and L-alanine and by exposure t

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https://doi.org/10.1007/978-0-387-88347-2. We have recently been able to document in isolated pancreatic endocrine cells removed from normal rats that an increase in extracellular D-glucose concentration provokes a rapid and sustained increase in cytosolic Ca. activity.. Several factors could contribute to this increase in cytosolic Ca. co

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