Titlebook: Biological Reactive Intermediates III; Mechanisms of Action James J. Kocsis,David J. Jollow,Robert Snyder Book 1986 The Editor(s) (if appli

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Klimazeugnisse der Erdgeschichteentity of their reactive metabolites, the chemistry of their covalent binding to cellular macromolecules and the relationship of the various types of covalent binding events to the biological changes which follow. This report summarizes some of our recent efforts toward these objectives.

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Das ?Wetter“ im Meer: Nord- und Ostseelerath et al., 1985; Guengerich et al., 1985). In the earlier efforts catalytic activity data were difficult to evaluate because most of the assays were not specific to individual P-450 isozymes (Wang et al., 1980, 1983). More recently we have focused our efforts on the biochemical characterization

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