Titlebook: Biological Barriers to Protein Delivery; Kenneth L. Audus,Thomas J. Raub Book 1993 Springer Science+Business Media New York 1993 biochemis

melancholy

書(shū)目名稱(chēng)Biological Barriers to Protein Delivery影響因子(影響力)




書(shū)目名稱(chēng)Biological Barriers to Protein Delivery影響因子(影響力)學(xué)科排名




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Adulterate

Ectopeptidasesly active peptides. These ectopeptidases are integral proteins of the plasma membrane, asymmetrically oriented, with the catalytic site exposed at the extracytoplasmic surface (see Fig. 1). For the majority of those ectopeptidases thus far characterized, the protein is anchored in the membrane by a

Directed

Condyle

Protein Uptake and Cytoplasmic Access in Animal Cells ways of delivering drugs into cells—for instance, with the purpose of irreversibly inhibiting the protein synthesis machinery of cancer cells—mechanisms by which various protein ligands are internalized by cells and subsequently translocated across the membrane of intracellular compartments are com

一回合

Transepithelial Transport of Proteins by Intestinal Epithelial Cellsn effective barrier to proteins and peptides. Epithelial cells play important roles in nutrition and mucosal immune defense apart from their simple function as a barrier, however, and some of these functions require transepithelial vesicular transport of intact macromolecules (Neutra and Kraehenbuhl

點(diǎn)燃

Intraoral Peptide Absorptionte of its apparent disadvantages such as limited absorptive surface and moderate mucosal permeability, this route of administration might be of benefit especially for small- or medium-size peptide drugs. Potential advantages for intraoral delivery are the avoidance of gastrointestinal or liver first

B-cell

疲憊的老馬

Dermal Absorption of Peptides and Proteinsd as a port for continuous systemic administration of drugs. The first transdermal drug delivery system which has used this new concept is a scopolamine-releasing transdermal therapeutic system (Transderm-Scop? by Ciba) for motion sickness. This was followed by the marketing of several nitroglycerin

deciduous

無(wú)王時(shí)期,