Titlebook: Biochemistry and Cell Biology of Ageing: Part IV, Clinical Science; J. Robin Harris,Viktor I. Korolchuk Book 2023 The Editor(s) (if applic

mechanism

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Melatonin and Aging,obally. While decline of many organ functions is an unavoidable concomitant of senescence, these can be delayed or moderated by a range of factors. Among these are dietary changes and weight control, taking sufficient exercise, and the utilization of various micronutrients. The utility of incurring

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Protein and Energy Supplements for the Elderly,otein energy malnutrition has shown to elevate morbidity and mortality risk in the elderly; therefore, protein and energy supplement are needed for the elderly populations to create healthy conditions. This chapter describes about general structure of protein, protein turnover, amino acid metabolism

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Clinical Ageing,chanistically, the lifelong accumulation of a wide range of molecular and cellular impairments leads to organismal senescence. The aging population poses a severe medical concern due to the burden it places on healthcare systems and the general public as well as the prevalence of diseases and impair

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Bone Cells Metabolic Changes Induced by Ageing,n bone mass, the appearance of specific changes in the local microarchitecture, a reduction in mineralized components and in load-bearing capacity, as well as the appearance of an abnormal response to different humoral molecules have been observed. The present review points out the most important da

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Chronic Kidney Disease and the Exposome of Ageing,disease and how this might be manipulated to improve health span..Notably, we discuss the manipulation of the foodome to mitigate acceleration of ageing processes by phosphate and to explore use of emerging senotherapies. A range of senotherapies, for removing senescent cells, diminishing inflammato

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Sarcopenia and Ageing,h emphasis on mitochondrial dysfunction, intramuscular fat infiltration and neuromuscular junction deterioration, and (3) current treatments with regard to physical exercises and nutritional supplement.