Titlebook: Biochemistry and Cell Biology of Ageing: Part IV, Clinical Science; J. Robin Harris,Viktor I. Korolchuk Book 2023 The Editor(s) (if applic

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Tendon Aging,ess has on tendons at the tissue, cellular, and molecular levels and briefly reviews potential biological predictors of tendon aging. Recent research findings that are herein reviewed and discussed might contribute to?the development of precision tendon therapies targeting the elderly population.

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Models and Biomarkers for Ovarian Ageing,es. The study of genetic and subcellular biomarkers for the ovarian reserve has produced less concrete results. Recent advances are described and compared in terms of limitations and potential. The chapter concludes with an overview of the future study indicated by our current knowledge and by curre

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Melatonin and Aging,f melatonin are especially relevant to many of the changes associated with senescence. Changes in functioning of the immune system are particularly marked in the aged, combining diminishing effectiveness with increasing ineffective and harmful activity. Melatonin treatment appears able to moderate a

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Clinical Ageing,r ageing. The question arises as to whether this is due to the intrinsic ageing of stem cells or, rather, to the impairment of stem-cell function in the aged tissue environment. The risk of having a stroke event doubles each decade after the age of 55. Therefore, it is of great interest to develop n

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https://doi.org/10.1007/978-3-031-53233-7n bone mass, the appearance of specific changes in the local microarchitecture, a reduction in mineralized components and in load-bearing capacity, as well as the appearance of an abnormal response to different humoral molecules have been observed. The present review points out the most important da

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Justice and Recovery for Victimised Childrendisease and how this might be manipulated to improve health span..Notably, we discuss the manipulation of the foodome to mitigate acceleration of ageing processes by phosphate and to explore use of emerging senotherapies. A range of senotherapies, for removing senescent cells, diminishing inflammato

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