Titlebook: Bioactive Sphingolipids in Cancer Biology and Therapy; Yusuf A. Hannun,Chiara Luberto,Lina Marie Obeid Book 2015 Springer International Pu

Counteract

Role of Sphingolipids in Non-melanoma Skin Cancerf cells that it originates from. Emerging evidence suggests that sphingolipids play an important role in regulating these cellular responses of keratinocytes and the homeostasis of the epidermis. In this review, we will discuss the role for sphingolipids and their metabolizing enzymes in regulating

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Dysregulation of Sphingolipid Metabolism in Melanoma: Roles in Pigmentation, Cell Survival and Tumortes and enzymes that contribute to this metabolic dysregulation in melanoma, to discuss the emerging roles of sphingolipids on melanogenesis, tumor microenvironment and melanoma progression, and to highlight relevant therapeutic approaches applicable for melanoma treatment.

Decline

Colon Cancer: The Role of Sphingolipid Metabolic Enzymes, suggesting that the balance between these potent bioactive lipids may dictate cell fate. In this chapter, we review the roles of these bioactive sphingolipids and their metabolic enzymes in colitis, colitis associated cancer, and colorectal cancer.

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