Titlebook: Bioactive Sphingolipids in Cancer Biology and Therapy; Yusuf A. Hannun,Chiara Luberto,Lina Marie Obeid Book 2015 Springer International Pu

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op novel cancer therapeutics. As well, the volume includes a critical examination of the specific pathways and pathobiologies associated with the altered regulation of sphingolipid metabolism as a contributor to the development and/or maintenance of pathological conditions such as cancer..978-3-319-35371-5978-3-319-20750-6

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流浪

Jesus in an Age of Enlightenmentung and head and neck cancers. Specifically, recent discoveries on the roles of sphingolipids in the regulation of head and neck squamous cell carcinoma and lung cancers will be discussed. Moreover, recent efforts on the identification of sphingolipid metabolism related biomarker development will be deliberated.

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Sphingolipids in the Pathogenesis of Head and Neck and Lung Cancers: Translational Aspects for Theraung and head and neck cancers. Specifically, recent discoveries on the roles of sphingolipids in the regulation of head and neck squamous cell carcinoma and lung cancers will be discussed. Moreover, recent efforts on the identification of sphingolipid metabolism related biomarker development will be deliberated.

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Book 2015udes discussions of the innovative techniques and approaches for quantitative analysis and imaging that could significantly impact the general understanding of this topic, and the potential benefit of targeting sphingolipid enzymes to develop novel cancer therapeutics. As well, the volume includes a

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Sphingolipids as Mediators of Breast Cancer Progression, Metastasis, Response and Resistance to Chemstance. In basal type breast tumors CERT and GCS play a role in resistance to taxanes suggesting that targeting these pathways may be an effective route for the treatment of aggressive triple negative tumors. The role of sphingolipids in Her2-like tumors has not been thoroughly studied. However, CER