Titlebook: Bacterial Activation of Type I Interferons; Dane Parker Book 2014 Springer International Publishing Switzerland 2014 Bacterial Pathogenesi

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978-3-319-38502-0Springer International Publishing Switzerland 2014

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https://doi.org/10.1007/978-3-030-84936-8auses of diseases. Immune responses against streptococci include the induction of type I interferons (IFNs), which are immunomodulatory cytokines with well-established antiviral functions, but ambiguous roles in bacterial infections. Studies of streptococcal infections further highlight the importan

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https://doi.org/10.1007/978-3-030-84936-8plication of influenza infection. The type I IFN pathway was initially characterized as a viral defense mechanism but it is now appreciated bacteria can also activate this response. This chapter gives an overview of the role type I IFNs play in the host response to infection with .. The role this pa

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Thermodynamic Properties of Plasmas. activates type I interferon (IFN) signaling through the release of lipopolysaccharide (LPS) from the bacterial surface. Interaction between LPS and the host receptor TLR4 initiates type I IFN through the adaptor proteins TRIF and IRF3. The role of type I IFN signaling during infection is unclear a