Titlebook: Bacterial Activation of Type I Interferons; Dane Parker Book 2014 Springer International Publishing Switzerland 2014 Bacterial Pathogenesi

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Activation of Type I IFN Signaling by ,,plication of influenza infection. The type I IFN pathway was initially characterized as a viral defense mechanism but it is now appreciated bacteria can also activate this response. This chapter gives an overview of the role type I IFNs play in the host response to infection with .. The role this pa

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The Detrimental Role of Type I Interferon Signaling During Infection with ,, to evade the defense mechanisms. During infection of mice with . serovar Typhimurium (.), which mimics the typhoid disease in humans, type I IFN signaling leads to rapid host fatality, and abrogation of this signaling leads to prolonged host survival. The detrimental role of type I IFN during . inf

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Induction and Function of Type I IFNs During Chlamydial Infection,e response to chlamydial infection is recognition of conserved microbial markers on . spp. by host pathogen recognition receptors (PRRs) on epithelial cells. This innate immune recognition leads to a host inflammatory response, a major mediator of the oviduct disease during . genital infection. Type

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