Titlebook: Aspartic Proteinases; Retroviral and Cellu Michael N. G. James Book 1998 The Editor(s) (if applicable) and The Author(s), under exclusive l

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Selection and Characterization of VX-478 Resistant HIV-1 Variantsol viral polypeptide. The kinetic data were interpreted with the aid of molecular modeling to understand the effect of mutations on inhibitor binding and processing of the gag-pol polypeptide to generate infective virions.

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gospel

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adhesive

Paul G. Fitzgerald,Marco G. Malusàmewhat primitive technologies. It had a renaissance of biochemical characterisation, followed by a classical period when sequences were defined and catalytic activity identified. It is now very much under the influence of the structural school. Thus, in many ways its history parallels that of painti

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Cas clinique: ?fistule de Crohn? and functional forms Since either genetic inactivation or chemical inhibition of the protease results in the production of non-infectious viral particles, the development of inhibitors of the HIV-1 protease has been pursued as a means of preventing viral replication. Although many inhibitors now ex

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Fistules anales: le traitement standards is via a blood-sucking insect. Equine infectious anaemia virus (EIAV) is closely related to other lentiviruses of ruminants and primates, such as HIV, SIV and FIV (feline immunodeficiency virus). Just as with these other viruses, EIAV encodes an aspartic proteinase which is essential for processin

IDEAS

Fistules anales: le traitement standardle of the virus. The great potential of HIV protease as a therapeutic target for treating the acquired immunodeficiency syndrome, AIDS, has now been confirmed by the recent success of HIV inhibitor drugs to suppress HIV propagation in clinical trials (Ho ., 1995; Wei .., 1995; Coffin, 1995). In spit