Titlebook: Artificial Nucleases; Marina A. Zenkova Book 2004 Springer-Verlag Berlin Heidelberg 2004 Catalysis.Cleavage.Conjugates.DNA.Enzyme mimics.N

即席演說

健談

V. Lange,G. Meyer,H. Rau,A. Mewesgested more than 30 years ago (Belikova et al. 1967). Since then, various oligonucleotide derivatives have been created which are capable of damaging nucleic acids and thereby influencing their function (Knorre et al. 1994). However, such oligonucleotide conjugates have not yet been applied as artif

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Dna262

Nucleic Acids and Molecular Biologyhttp://image.papertrans.cn/b/image/162708.jpg

custody

P. G. Friedl,G. Schürmann,Ch. Herfarthles. This simplicity appears to be an advantage when artificial RNases are used in design of therapeutics for controlling gene expression or as components of synthetic conjugates. These conjugates are targeted to specific RNA molecules by oligonucleotides, and unwanted interactions of their componen

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ALERT

V. Lange,G. Meyer,H. Rau,A. Mewes footprinting experiments to analyze the structure of protein-nucleic acid complexes. These cleavage reagents have also been tethered to larger molecules such as oligonucleotides, proteins, and intercalating agents, which confer additional specificity. This review will focus on the 1,1O-phenanthroli

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0933-1891 s. The second class, artificial nucleases, are rationally designed to imitate the active centers of natural enzymes by simple structures possessing minimal sets o978-3-642-62139-0978-3-642-18510-6Series ISSN 0933-1891 Series E-ISSN 1869-2486