Titlebook: Anxiety and Anxiolytic Drugs; Florian Holsboer,Andreas Str?hle Book 2005 Springer-Verlag Berlin Heidelberg 2005 Anxiety.Anxiolytic Drugs.N

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Anxiety Disorders: Noradrenergic Neurotransmission,earch pertinent to the neurobiological basis of anxiety disorders. The implications of this synthesis for the discovery of anxiety disorder vulnerability genes and novel psychopharmacological approaches will also be discussed.

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Excitatory Amino Acid Neurotransmission,nd 2,3-benzodiazepines also show more promise than e.g. competitive antagonists. Great progress has also been made in the field of metabotropic glutamate receptors since the discovery of novel, allosteric modulatory sites for these receptors. Selective agents acting at these transmembrane sites have

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Neurobiology and Treatment of Anxiety: Signal Transduction and Neural Plasticity,es for additional signaling pathways; however, less is known about such mechanisms in anxiety. The challenge to identify intracellular signaling pathways and related molecular and structural changes that are critical to the etiology and treatment of anxiety will further establish the importance of m

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Pharmacogenomics,In order to know whether they can be extrapolated to patients with anxiety disorders, clinical studies are warranted. Despite all the shortcomings of the currently available pharmacogenetic studies, this field holds great promise for the treatment of anxiety disorders. In the future, psychiatrists m

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Learning and Memory,tic stress disorder. Basic research performed in laboratory animals may help to elucidate the aetiology of the respective diseases. This chapter gives a short introduction into theoretical and practical aspects of animal experiments aimed at investigating acquisition, consolidation and extinction of

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