Titlebook: Antisense Therapeutics; Sudhir Agrawal Book 19961st edition Humana Press 1996

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Electron Spin Relaxation in Liquid Crystals,enetic disorders because of their ablhty to inhibit expression of a disease-associated gene in a sequence-specific manner. Gene expression is inhibited by hybrid ization of the oligonucleotide to sequences in the gene or the messenger RNA (mRNA) target by Watson-Crick base pairing. The first example

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Electron Spin Relaxation Phenomena in Solidsherapeutic agent. in principle, an antisense oligonucleotide targeted at a gene essential for neoplastic cell growth should interfere with only that gene’s expression, resulting in arrest of cancer cell growth.

MURAL

H. I. Starnberg,H.E. Brauer,H. P. HughesBiological science is a rapidly flowing experimental stream, at times encountering a dam that impedes further progress. At such a pomt, a single crack may induce a major breakthrough Discovery of the double helical structure of DNA in 1953 (.) caused such an event, with flooding of new information into the area now known as molecular biology.

POINT

History of Antisense Oligonucleotides,Biological science is a rapidly flowing experimental stream, at times encountering a dam that impedes further progress. At such a pomt, a single crack may induce a major breakthrough Discovery of the double helical structure of DNA in 1953 (.) caused such an event, with flooding of new information into the area now known as molecular biology.

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