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Titlebook: Antisense Therapeutics; Sudhir Agrawal Book 19961st edition Humana Press 1996

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期刊全稱Antisense Therapeutics
影響因子2023Sudhir Agrawal
視頻videohttp://file.papertrans.cn/159/158677/158677.mp4
學(xué)科分類Methods in Molecular Medicine
圖書封面Titlebook: Antisense Therapeutics;  Sudhir Agrawal Book 19961st edition Humana Press 1996
影響因子Leading researchers offer an authoritative survey and analysis of the latest findings on the rapid development of antisense oligonucleotides therapeutic and their application in various in vivo model systems. The book‘s high-profile contributors provide timely accounts of their state-of-the-art strategies, discussing such topics as the synthesis and purification of oligonucleotides, their selection for a particular gene target, different methods of administration, and the use of various cell lines and cell culture systems. They also examine questions of cellular uptake, in vitro biological activity, in vivo biological activity, the pharmacology and pharmacokinetics of oligonucleotides, and the application of oligonucleotides to the central nervous system.
Pindex Book 19961st edition
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Electron Spectroscopy for Surface Analysisviding important insights into their roles in tumorigenesis or normal growth and development (.–.). Although attention has been focused recently on the development of antisense ODN as therapeutics for a variety of diseases, including cancer (.), systemic application of ODN to treat tumors other than
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https://doi.org/10.1007/978-1-4613-2901-5human diseases, a major problem is that most extracellular compartments are constantly mixing with the blood, lymph, cerebrospinal fluid (CSF), and so forth, and thus constantly diluting the oligonucleotide. A possibly unique exception to this problem is the vitreous, a gelatinous fluid overlying th
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Band-Structure Calculation Methods,signs and symptoms of viral infections are frequently caused by the expression or overexpression of the acquired genes. Based on this basic concept, such acquired genetic diseases should be amenable to treatment by a specific block of gene expression. Gene expression can be blocked at different leve
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