Titlebook: Antidepressants: Past, Present and Future; Sheldon H. Preskorn,John P. Feighner (President an Book 2004 Springer-Verlag Berlin Heidelberg

凹槽

https://doi.org/10.1007/978-3-642-18500-7antidepressants; brain; depression; depressive disorder; drug; drug development; genomics; kinetics; persona

LUT

Complement

https://doi.org/10.1007/978-3-662-07024-6re development of antidepressants. However, attempts to describe the influences of drugs on brain and neuronal function have become increasingly complex, and it is now clear that neuronal processes are complex molecular events involving multiple control factors. The brain consists of approximately 1

鉆孔

https://doi.org/10.1007/978-3-662-07024-6f-life and steady-state concentration, and linear versus nonlinear pharmacokinetics. Factors that can affect the pharmacokinetics of a drug include protein binding, cardiac function and hepatic arterial blood flow, hepatic integrity, renal factors, aging, disease, and gender. An understanding of bas