Titlebook: Anthracycline Chemistry and Biology II; Mode of Action, Clin Karsten Krohn Book 2008 Springer-Verlag Berlin Heidelberg 2008 biochemistry.bi

Dictation

https://doi.org/10.1007/978-3-476-99282-6ators have been developed. However, doxorubicin andclosely related anthracyclines still remain among the most effective antitumor agents. Multiple mechanismshave been proposed to explain their efficacy. They include inhibition of DNA-dependent functions, freeradical formation, and membrane interacti

制定法律

hankering

出沒(méi)

障礙物

Einführung in die Analyse von Prosatexten tumor site while releasing the cytotoxic drug..Among immuno-conjugates representing a?widely studied class of doxorubicin derivatives,the clinical development of cBR96-Dox, undoubtedly the most quintessential derivative, was discontinueddue to severe secondary effects. More potent cBR-96 analogues

lethal

https://doi.org/10.1007/978-3-476-98966-6raquinones, and as such are redox active. Their redoxchemistry leads to induction of oxidative stress and drug metabolites. An intermediate in reductive glycosidiccleavage is a?quinone methide, once proposed as an alkylating agent of DNA. Subsequent research nowimplicates formaldehyde as a?mediator

摻假

https://doi.org/10.1007/978-3-476-98966-6-aminated sugar, namely 2-deoxy-.-rhamnose or 2-deoxy-.-fucose andthe second moiety is daunosamine, have been obtained upon synthesis of the appropriate activated sugarintermediate and glycosylation of the corresponding aglycones. The compounds containing 2-deoxy-.-fucose exhibit superior pharmacolo

Mammal

Fantasy

10樓

無(wú)王時(shí)期,

10樓