Titlebook: 25 Years of p53 Research; Pierre Hainaut,Klas G. Wiman Book 2005 Springer Science+Business Media B.V. 2005 DNA.P53, Wiman, Hainaut, tumor

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Prognostic and Predictive Value of TP53 Mutations in Human Cancer,978-0-230-23947-0

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Lucia Knap?íková,Dragan Perakovi?scientists thought to find a common ground between concepts generated in each field. Thirdly, the study of mouse genetics demonstrated that some cancers were clearly inherited and these observations confirmed many prior publications that suggested a role for cancer causing genes in humans and other

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Lecture Notes in Mechanical Engineering much research has focused on understanding this crucial ability as well as its regulation. Indeed, the regulation of p53 DNA binding has generated much debate recently, specifically with regard to the role of the C-terminus.

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Pragmatic Performance Managementvation of p53 in normal tissues, however, can lead to tissue damage and has been associated with multiple sclerosis (Wosik et al., 2003), neurodegenerative disorders and exacerbation of ischemic damage from stroke or cardiac arrest (Mattson et al., 2001; Komarova and Gudkov, 2001). Accordingly, the

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