Titlebook: Vitamin D; Physiology, Molecula Michael F. Holick Book 19991st edition Humana Press 1999 Absorption.Calcium.Metabolite.Public Health.Vitami

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2628-197X al because each includes: a synthesis of the state of the science; timely, in-depth reviews by the leading researchers in their respective fields; extensive, up-to-date fully annotated reference lists; a detailed index; relevant tables and figures; identification of paradigm shifts and the consequen

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The Enzymes Responsible for Metabolizing Vitamin D,n the skin from 7-dehydrocholesterol, a precursor of cholesterol, by the action of ultraviolet light .. It is then transported to the liver and is hydroxylated at position 25 by vitamin D. 25-hydroxylase (25-hydroxylase) to 25-hydroxyvitamin D. [25(OH)D.]. The 25(OH)D. formed is again transported to

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Molecular Biology of the Vitamin D Receptor,ne physiology is most apparent in the deficiency state, in which the lack of vitamin D produces rickets in children and osteomalacia in adults. However, vitamin D is more appropriately classified as a hormone, and it is the vitamin D endocrine system that regulates skeletal homeostasis. In response

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Vitamin D Receptor Translocation,arates the nucleus from the cytoplasm, and the nuclear pore complex (NPC) is the site of exchange between the two compartments Small molecules may pass through the NPC by diffusion, but macromolecules that are larger than 20 kDa cannot enter the nucleus by passive diffusion. Transport of large prote