Titlebook: Viruses and Human Cancer; S. David Hudnall Book 2014 Springer Science+Business Media New York 2014 infectious diseases

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,Epstein–Barr Virus: Epidemiology and Clinical Features of Related Cancer,assure its survival and lifelong persistence in the human host. In the vast majority of infected hosts, EBV remains in a nearly silent latent state that remains asymptomatic throughout life. In contrast, in the immunodeficient host, EBV infection can lead to severe disease ranging from organ failure

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Hepatitis C Virus: Pathogenesis and Host Immune Response,es play unique roles in the viral life cycle and pathogenesis. The virus life cycle also requires the cooperation of host cell factors. The low proofreading capacity of the viral RNA polymerase ensures a high level of variation, leading to the selective development of new genotypes, subtypes, and qu

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Hepatitis B Virus: Pathogenesis and Host Immune Response,nduced end-stage liver disease and liver cancer. Mechanisms from acute hepatitis B virus (HBV) infection progress into chronicity, repeated bouts of inflammations were reviewed, with emphasis on the unusual modest innate immune responses against the virus. Chronic inflammation paves the way for mali

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Hepatitis B Virus: Epidemiology and Clinical Features of Related Cancer,nt cause of the tumor. This virus is endemic in resource-constrained geographical regions. HBV-induced HCC occurs commonly in these regions, but rarely in resource-rich regions. The chronic viral infection responsible for the tumor is acquired by either perinatal transmission or horizontal infection

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Human Papillomavirus: Pathogenesis and Host Immune Response, in prevention with the development of vaccines, there remains a need for further research to help those who are already infected and those for whom vaccination is not an option. Additionally, the mechanism of HPV-associated oncogenesis can provide mechanistic clues for other, non-HPV-associated can

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Human Papillomavirus: Epidemiology and Clinical Features of Related Cancer,symptomatic; however, the spectrum of virus-associated conditions ranges from warts, such as verruca vulgaris and genital warts, to malignancies such as cervical and anogenital cancers. Many of the conditions display distinguishable clinical features that aid in diagnosis. Patterns of infection can

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Human T-Cell Leukemia Virus Type 1: Epidemiology and Clinical Features of Related Cancer,eukemia/lymphoma (ATLL) by Takatsuki and his colleagues in 1977. The leukemia cells in patients were characterized by unusual morphology with ovulated nuclei, which were named “flower-like cells.” These abnormal cells were soon identified as T cells expressing interleukin 2-receptor (IL-2R/CD 25) at