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Titlebook: Viral Expression Vectors; Nicholas Muzyczka (Associate Professor) Book 1992 The Editor(s) (if applicable) and The Author(s), under exclusi

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發(fā)表于 2025-3-21 18:00:46 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Viral Expression Vectors
編輯Nicholas Muzyczka (Associate Professor)
視頻videohttp://file.papertrans.cn/984/983187/983187.mp4
叢書名稱Current Topics in Microbiology and Immunology
圖書封面Titlebook: Viral Expression Vectors;  Nicholas Muzyczka (Associate Professor) Book 1992 The Editor(s) (if applicable) and The Author(s), under exclusi
描述In the past ten years there has been enormous progress in the development of eukaryotic viral vectors. In general, these vectors have been developed for one of three reasons: to achieve high levels of expression of a particular gene product (poxvirus, baculovirus, and adenovirus), to clone eukaryotic genes in combination with functional assays (Epstein-Barr virus), of for use as delivery vehicles for the stable introduction of foreign genes into mammalian cells (retroviruses, Epstein-Barr virus, and adeno-associated virus). Each vector has its strengths and weaknesses that are rooted in the sometimes bewildering stra- tegies that the parent viruses use for propagation. No one of these vectors is appropriate for all of the problems that a mole- cular biology laboratory is likely to encounter, and few of us are knowledgeable in the molecular virology of all of these viruses. This volume represents an attempt by the authors to assem- ble a review of these vectors in one place and in a form useful to laboratories that do not necessarily have experience with eukaryotic viruses. Clearly, any virus can be modified to serve as a vector for some purposes, and it was not possible to include
出版日期Book 1992
關鍵詞Baculoviren; Impfstoffe; Retroviren; Vaccinia; Viren; biology; cell; gene; gene expression; genome; insects; re
版次1
doihttps://doi.org/10.1007/978-3-642-75608-5
isbn_softcover978-3-642-75610-8
isbn_ebook978-3-642-75608-5Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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Retroviral Vectors,h utilize the efficient gene transfer capability that retroviruses have evolved. The advantages of currently available retroviral vectors include the ability to efficiently infect a wide range of cell types from different animal species, the precise integration of genetic material carried by the vec
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Poxvirus Expression Vectors,, was responsible for smallpox, one of the most dreaded of all infectious diseases. In the late 18th century, Edward Jenner demonstrated that smallpox could be prevented by immunization with a more benign relative, vaccinia virus, which caused mild infections in cattle. Ultimately, global vaccinatio
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Epstein-Barr Virus Based Expression Vectors,nd is by no means mature (for contrast see the reports from the first and second Banbury Conferences on Eukaryotic Viral Vectors, G. 1982; G. and H. 1988). Although in theory it should be possible to develop a eukaryotic vector from any virus, practical considerations have led to concentration on a
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