Titlebook: Vertebrate Development; Maternal to Zygotic Francisco Pelegri,Michael Danilchik,Ann Sutherland Book 2017 The Editor(s) (if applicable) and

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Egg Activation at Fertilization,ivates the egg, i.e., it causes a series of changes that are required for the initiation of embryo development. This is achieved by triggering an elevation in the egg’s intracellular free calcium concentration. In response, the fertilized egg completes meiosis and enters the first embryonic cell cyc

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Controlling the Messenger: Regulated Translation of Maternal mRNAs in , Development,chanisms, but while some of the mRNAs under consideration at these stages encode cell-fate determinants, many encode cell cycle regulatory proteins that drive these early cell cycles. In contrast, while maternal mRNAs encoding key . (i.e., cell-fate) regulators that function after the first cleavage

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Vertebrate Embryonic Cleavage Pattern Determination,generated by the cleavage furrow for the previous cell cycle. Also explored are mechanisms that integrate cell division given the limited supply of cellular building blocks in the egg and several-fold changes of cell size during early development, as well as cytoskeletal specializations specific to

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Localization in Oogenesis of Maternal Regulators of Embryonic Development,m cell determinants to the vegetal pole, from where they redistribute to the cleavage furrows of the 2- and 4-cell stage embryo, ultimately specifying the primordial germ cells (PGCs). The sperm entry region during fertilization is also defined by the AV axis. In frogs and fish, sperm enters through

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Wei-Chia Tseng,Mumingjiang Munisha,Juan B. Gutierrez,Scott T. Dougan