Titlebook: Vascularization for Tissue Engineering and Regenerative Medicine; Wolfgang Holnthoner,Andrea Banfi,Heinz Redl Living reference work 2020La

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Vascularization for Tissue Engineering and Regenerative Medicine978-3-319-21056-8

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Angiogenesis: Basics of Vascular Biology,f angiogenesis is enforced by postnatal vasculogenesis, which represents the recruitment of circulating true endothelial progenitor cells (late outgrowth EPCs or endothelial colony forming cells) to an area in need of blood supply, and is further supported by recruitment of myeloid early-outgrowth E

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Stimulation by Light,ich are involved in the vessel formation process. It triggers the activation of cytochrome c oxidase, which leads to the production of NO, ROS, and ATP in the mitochondria. These molecules appear to act as secondary messengers initiating ERK/Sp1 and PI3K signaling pathway, which in turn leads to pro

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Approaches for Generation of Lymphatic Vessels,c vasculature. Several regenerative approaches describe the stimulation of lymph vessel growth in vivo. Although the methods developed so far hold promise for the clinical use of engineered lymphatics, the optimal parameters for lymphatic engineering remain a challenge for future studies.

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In Vitro and In Vivo Approaches for Pre-vascularization of 3-Dimensional Engineered Tissues,hamber space which was capable of growing with and supporting the survival of tissue/organ specific cells implanted in the chamber. There was a time lag to development of this pedicle-based angiogenic network, and in recent years a new technique termed . has been developed that involves co-culture o

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From Autologous Flaps to Engineered Vascularized Grafts for Bone Regeneration, independently developed could be combined towards the prefabrication of vascularized tissues. The resulting paradigm of “regenerative surgery,” here exemplified in the specific context of bone regeneration, could represent the future standard for the reconstruction of complex body parts.