Titlebook: Vascular Mechanobiology in Physiology and Disease; Markus Hecker,Dirk J. Duncker Book 2021 Springer Nature Switzerland AG 2021 mechanobiol

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Hemodynamic Control of Endothelial Cell Fates in Development,ature. Blood flow determines the final expression pattern of arteriovenous markers and guides the pruning of excess vasculature, including the restructuring of the six pairs of aortic arches. Changes in blood flow can overrule arterial, venous, and lymphatic fates, causing both morphological and gen

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follicular-unit

Mechanobiology of Lymphatic Vessels,ry circulatory system is frequently overlooked. This system is called the lymphatic system, which serves to perform three primary functions in the human body: (1) drainage of interstitial fluid, (2) transport of immune cells, and (3) transport of lipid. These three functions are performed with the h

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Mechanical Regulation of Epigenetic Modifications in Vascular Biology and Pathobiology,sion and function in vascular cells, including endothelial cells (ECs) and smooth muscle cells (SMCs), thus affecting vascular biology in health and pathobiology in disease. Epigenetics refers to the study of sequence-independent heritable DNA alterations that modulate gene expression, including DNA

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Mechanobiology of Arterial Hypertension,ntial wall stress that is returned toward control by adaptive mechanisms such as active constriction and eutrophic remodeling with concomitant increases of wall thickness. However, other hemodynamic, mechanical stresses are enhanced by such adaptive responses. Specifically, wall shear stress rises b

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Mechanobiology of Atherosclerosis,issue structures contribute to cell differentiation, physiology, initiation, and progression of disease development. This review surveys new findings and progress in the research field of atherosclerosis in recent years. Moreover, it aims?to integrate different aspects to demonstrate the interlacing

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Book 2021his fascinating, timely and clinically highly relevant field. Mechanotransduction, mechanosensing, fluid shear stress, hameodynamics and cell fate, are just a few topics to name. All important aspects of vascular mechanobiology in health and disease are reviewed? by some of the top experts in the fi