Titlebook: Vascular Anomalies; A Guide for the Hema Cameron C. Trenor III,Denise M. Adams Book 2020 Springer Nature Switzerland AG 2020 rare vascular

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Nomenclature of Vascular Anomalies: Evolution to the ISSVA 2018 Classification System,cine, with increasing interest in the biology, etiology, genetics, clinical behavior, and treatment of these disorders. Despite this growing fascination, incorrect nomenclature plagues the medical literature and clinical practice. The chronology of classification schemas for vascular anomalies paral

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Diagnosis of Vascular Anomalies,ntified in the course of evaluation for a thrombotic event. Though the majority of vascular anomalies are not malignant, many are associated with significant morbidity and mortality. Accurate diagnosis is important in order to predict clinical course, guide the search for associated features, and ch

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The Genetic Basis of Vascular Anomalies,y of vascular anomalies form sporadically, the rare familial cases expedited understanding the pathogenesis of vascular anomalies. The identification of genes that have been mutated identified the signaling pathways that are involved, thereby providing potential therapeutic targets. The puzzling que

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Sirolimus for the Treatment of Vascular Anomalies,eld is more precise in the phenotypes of these disorders. The discovery of germline and somatic genetic mutations has led to a better understanding of the genotypes involved and phenotypic?correlation for most vascular anomalies. Many of these mutations occur in the same cellular signaling pathways,

archaeology

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Kaposiform Hemangioendothelioma and Kasabach-Merritt Phenomenon: Management of Coagulopathy and Treh a vascular anomaly was termed the Kasabach-Merritt phenomenon (KMP). However, with improved understanding of disease pathophysiology and histology, subcategories of vascular tumors are now better defined. Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor with two distinctive features:

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Rare Vascular Tumors,nto benign, locally aggressive rare vascular tumors and malignant vascular tumors. This improved classification schema has resulted in accurate diagnosis and appropriate management algorithms. This chapter describes benign, locally aggressive rare tumors and malignant vascular tumors found in childr

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Venous Malformations and Associated Syndromes: Diagnosis and Management,hey can involve deeper structures. Venous malformations are associated with other vascular anomaly syndromes as well. Common presenting symptoms include swelling, pain, mass effect, and psychosocial stressors. Coagulopathy is observed with diffuse and multifocal lesions. Ultrasonography and magnetic

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Lymphatic Anomalies,ymphaticovenous anastomosis, updated ISSVA classification, discoveries of PIK3CA and NRAS mutations, and the use of sirolimus to control complications of lymphatic anomalies. Despite significant progress in the diagnosis and multidisciplinary management of lymphatic anomalies, significant unmet need

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