Titlebook: Urothelial Carcinoma; Methods and Protocol Wolfgang A Schulz,Michèle J. Hoffmann,Günter Niegi Book 2018 Springer Science+Business Media LLC

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Spheroid Cultures of Primary Urothelial Cancer Cells: Cancer Tissue-Originated Spheroid (CTOS) Methotrategies and in endeavors to overcome therapy resistance. Primary cultures of cancer cells acutely dissected from individual patients can provide a platform that enables the study and characterization of individual tumors. To that end, we have developed a method for preparing cancer cells in the fo

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The N-butyl-N-4-hydroxybutyl Nitrosamine Mouse Urinary Bladder Cancer Model, occupational exposure, and genetic factors..UBC exhibits considerable genotypic and phenotypic heterogeneity. Among all UBC lesions, urothelial carcinoma is the most frequently observed histological type. Despite all the developments made in urologic oncology field, therapeutic options remain inad

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Patient-Derived Bladder Cancer Xenograftse models retain the histological and genetic characteristics of the primary tumor and are considered a valuable platform for translational cancer research. This chapter describes the methodology to establish and propagate bladder cancer PDX model.

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Algorithm for the Automated Evaluation of , Genotypes genotyping and present a program based on Microsoft. Access. which automatically generates all possible haplotype pairs for a given unphased . genotype. .?haplotypes are important to predict the . phenotype.

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Orthotopic Mouse Models of Urothelial Cancercompetent mice. Current techniques rely on inoculation by intravesical instillation or direct injection into the bladder wall. Alternative models include the induction of murine bladder tumors by chemical carcinogens (BBN) or genetic engineering (GEM).

Aviary

1064-3745 ation advice from the experts.Includes supplementary materia.This volume details standard techniques for the characterization of urothelial carcinoma as well as methods to investigate mechanisms of carcinogenesis.? Chapters guide readers on cellular and animal models for urothelial carcinoma and rel