Titlebook: Understanding Depression; Volume 1. Biomedical Yong-Ku Kim Book 2018 Springer Nature Singapore Pte Ltd. 2018 Pharmacogenetics.Imaging genet

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Imaging Genetics Studies on Susceptibility Genes for Major Depressive Disorder, the Present and the symptoms. Therefore, intermediate phenotypes of neuroanatomical nature in MDD have been detected by imaging techniques. In order to evaluate the impact of genetic variation on behavior-related psychiatric symptoms, imaging genetics has been applied in various psychiatric disorders. Numerous studies

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miRNAs As Critical Epigenetic Players in Determining Neurobiological Correlates of Major Depressive ive disorder (MDD). Risk factors associated with adverse environmental condition are mostly found to be influential in pattering the neuromolecular architecture and functional output of depressed brain. Improper functioning of plasticity-related genes and stress-associated factors are often consider

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Complex Role of the Serotonin Receptors in Depression: Implications for Treatments of major depressive disorder. Recent investigations further supported the notion of their interaction with the antidepressant medication and advanced the knowledge on underlying mechanisms of their action. The heterogeneous properties of individual 5-HT receptors offer a chance for development of

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Biological Markers to Differentiate the Subtypes of Depression course of illness, and response to pharmacotherapy. It is assumed that this heterogeneity stems from different biological mechanisms per MDD subtype. Based on this, MDD has been clinically classified into melancholic [characterized by the presence of psychomotor disturbance and strong relationship