Titlebook: Understanding Depression; Volume 2. Clinical M Yong-Ku Kim Book 2018 Springer Nature Singapore Pte Ltd. 2018 Major depression and bipolar d

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Depression in DSM-5: Changes, Controversies, and Future Directionspecifiers, severity assessments, and cross-cutting symptom measure assessments, depressive disorders in DSM-5 are still diagnosed and classified based largely on categorical approaches. Moreover, the heterogeneity of MDD in terms of a polythetic operational diagnosis has been characterized as corres

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Major Depressive Disorder and Bipolar Disorder: Differentiating Features and Contemporary Treatment e bipolar diathesis is a much more severe condition and is difficult to diagnose as it tends to masquerade in myriad forms. Since current treatments are palliative rather than curative in nature, there is an urgent need to foster a better understanding of the underpinning pathogenic mechanisms and d

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Biomarkers of Depression: Potential Diagnostic Toolsedict and confirm the MDD diagnosis. Reliable panel or a set of biomarkers, when developed, will have a significant clinical use, to lead toward the personalized treatment strategies, and might reduce health costs, DALYs, and decrease disease burden.

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Pathophysiological Voice Analysis for Diagnosis and Monitoring of Depressionthe other hand, studies using the fundamental frequency (F0) which is obtained as a lowest frequency by FFT also have been reported. F0 is affected vocal cord vibration, and currently there are various methods of F0 analysis. F0 contains a lot of involuntary components compared to the formant. There

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Sleep and Sleep Disorders in Depression may be related to a predominance of cholinergic activity relative to monoaminergic activity. For patients with depression who experience insomnia, antidepressants, hypnotics, and cognitive behavioral therapy can be used effectively to relieve insomnia. However, since pharmacotherapy for depression

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Chronobiology and Treatment in Depressiondvance. Melatonin is efficient as an adjuvant treatment in unipolar or bipolar MDD when insomnia or delayed phase syndrome is associated. Psychotherapies focused on sleep or rhythms (IPSRT, CBT-I) are effective on sleep disorders, depressive symptoms, and the prevention of depressive relapses. The c

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